Histopathology reporting software, from grossing to signed report
Histopathology reporting software has to keep track of far more than a result: every biopsy needs a case number, a gross description, a set of blocks and slides that must never get lost, a microscopic description and a diagnosis signed by the pathologist, sometimes with an addendum weeks later. PathLab Software handles histopathology and cytology cases inside the same LIS your lab already uses for routine tests, at small-lab prices in India.
What does histopathology reporting software need to handle?
A small histopathology bench usually runs on a register, Word templates and a cabinet of blocks. The weak points are always the same: a case number written twice, a block that cannot be found when a second opinion is requested, a Pap smear category typed differently by two pathologists, and no way to show an assessor how long biopsies take. Software for this bench should cover:
- Case numbers per case type and year that never repeat (H/26/0412 for histopathology, C/ for Pap and fluids, F/ for FNAC, FS/ for frozen sections).
- Gross descriptions from templates, so the routine 80 % takes seconds and the pathologist types only the measurements.
- Blocks and slides labelled consistently, with stains, recuts, status and archive location.
- Microscopy and diagnosis from templates or free text, with standard categories for cytology.
- Sign-off by the pathologist only, with the same fingerprint and QR verification as routine reports.
- Addenda that are dated, logged and visible to anyone who checks the report later.
- Turnaround time by case type against the lab's own targets, with overdue cases flagged.
- An issue log for blocks and slides sent out for second opinion and brought back.
How a biopsy moves through PathLab Software
- Receive and number the case. When a histopathology or cytology test is received, a case is created with its number, for example H/26/0412, from a per-year sequence. Record specimen, site, laterality, number of containers, fixative and clinical history; an unacceptable specimen (unlabelled, unfixed) is rejected straight into the sample rejection register.
- Gross with a template. On the Gross tab, type a short code and a space to expand the template, then fill the blanks.
- Log blocks. Add blocks per container; they are labelled A1, A2, A3, and B1 onwards for a second container. Each block has tissue description, stains (H&E by default, plus special stains or IHC lines), slide count, recut flag and status from embedded to archived.
- Print labels. One click prints block and slide labels with the case number, block label, stain, patient initials and a QR code, on plain paper or a label printer, from the browser.
- Microscopy and diagnosis. Use microscopy and diagnosis templates or free text. Pap and thyroid FNAC cases pick a category; any case can be flagged "malignant / suspicious" for follow-up.
- Submit and sign. Submission is blocked while the diagnosis is empty. The pathologist signs from the case page or the validation queue, on a desktop or a phone.
- Archive, issue or add an addendum. Blocks get a cabinet and drawer location; blocks sent for second opinion are logged out and back. A dated addendum can be added after sign-off.
Grossing with templates
Typing .gb followed by a space in the gross box expands the lab's gallbladder template: "Received in formalin a gallbladder measuring {size} cm. Serosa {serosa}. Wall thickness {wall} cm. Mucosa {mucosa}. Calculi: {calculi}. Representative sections: A1 fundus, A2 neck with cystic duct margin, A3 body." The first blank is selected, so the pathologist types the size; the Tab key jumps to the next blank. Starter templates for appendix, gallbladder, endometrial curettings, skin punch and cervical biopsy are included for your pathologist to review and adapt, and your lab can add its own for any specimen.
Block and slide log
| Block | Tissue | Stain | Slides | Status | Location |
|---|---|---|---|---|---|
| A1 | Gallbladder wall, fundus | H&E | 1 | Archived | Cabinet 3 / Drawer 2 |
| A2 | Neck with cystic duct margin | H&E | 1 | Archived | Cabinet 3 / Drawer 2 |
| A3 | Wall, body | H&E + PAS | 2 | Issued to second opinion (returned 02 Nov) | — |
What should a histopathology report contain?
The exact layout is your lab's choice, but a complete histopathology report usually has the parts below. PathLab Software prints them in this order on the signed report, under the same lab header and QR verification as your routine reports.
| Section | What it contains | Where it comes from in PathLab Software |
|---|---|---|
| Header | Lab name, case number, report number, dates received and reported | Case number from the per-year sequence; report number at sign-off |
| Patient and requester | Name, age, sex, MRN, referring doctor | Registration and order |
| Specimen | Specimen type, site, laterality, number of containers, fixative | Details tab |
| Clinical details | History and clinical question from the requisition | Details tab (pre-filled from the order notes) |
| Gross description | Measurements, appearance, sections taken, with block key | Gross tab and block log |
| Microscopy | Microscopic description; synoptic checklist if used | Microscopy and Synoptic tabs |
| Diagnosis | Clear final diagnosis; cytology category where relevant | Diagnosis field and category list |
| Comments | Recommendations, correlation, special stains or IHC performed | Diagnosis text and block stain lines |
| Sign-off | Pathologist's name, qualification, registration number, date and time | Electronic signature, SHA-256 fingerprint, QR code |
| Addenda | Dated additions after sign-off, with the reason | Addendum on the Report tab; report marked amended |
Synoptic checklists are built by your lab from simple rows (label, type, options). CAP cancer protocols are not shipped; build the checklists your protocol requires.
Cytology: Pap smear and FNAC with standard categories
Cytology cases live in the same board. Pap smears and fluid cytology get C numbers and FNACs get F numbers, so the case register stays readable. For a Pap smear the pathologist records specimen adequacy and picks a category from the list used by The Bethesda System for Reporting Cervical Cytology: NILM, ASC-US, ASC-H, LSIL, HSIL, squamous cell carcinoma, AGC, AIS, adenocarcinoma or other malignant neoplasm. For a thyroid FNAC the list is the Bethesda System for Reporting Thyroid Cytopathology categories I to VI (nondiagnostic, benign, atypia of undetermined significance, follicular neoplasm, suspicious for malignancy, malignant); other FNAC sites use free text. The chosen category prints on the report in full words, so two pathologists never phrase the same category differently.
Category lists and templates are starter content: review them with your pathologist before use. The pathologist's diagnosis is always the authority; software lists support it.
Turnaround time by case type
The case board shows a "TAT by case type" panel: for the last 90 days, the number of reported cases, the median and the 90th-percentile hours from receipt to sign-off, and your target. Default targets are 72 hours for a small biopsy, 120 hours for a large specimen, 72 hours for a Pap smear, 24 hours for FNAC, 48 hours for fluid cytology and 30 minutes for a frozen section; they are your lab's own and editable. Cases past their target carry an "Overdue" badge on the board.
| Case type (sample data) | Cases | Median (h) | P90 (h) | Target (h) |
|---|---|---|---|---|
| Small biopsy | 38 | 51 | 70 | 72 |
| Large specimen | 14 | 88 | 131 | 120 |
| Pap smear | 61 | 44 | 66 | 72 |
| FNAC | 22 | 9 | 20 | 24 |
Sample data. The same TAT figures feed the post-analytical quality indicators.
Blocks sent for second opinion: the issue log
When a block or slide set leaves the lab for a second opinion or IHC at another centre, the block row records who it was issued to and when. Until it comes back it shows as "issued, not returned", and the block archive has a filter for exactly that list, so a missing block is noticed in days, not at the next audit. When it returns, one tick records the return date and the block goes back to its archive location.
Signing from a phone, addenda and the QR check
PathLab Software runs in any phone browser, so a consultant pathologist who reports for several labs can review the case and sign without being at the bench. The signed report gets the same SHA-256 fingerprint and QR verification code as routine reports; see how verification works on the sample report. If a diagnosis needs to be added to later, for example after IHC, the pathologist adds a dated addendum. The report is marked amended, its fingerprint is recomputed, the change is logged in the audit trail, and the QR verification page shows the report as amended, which is the kind of record the NABL software page maps to ISO 15189. The optional AI report assistant never signs anything: drafts stay pathologist-reviewed.
How does it compare?
| Task | Register + Word | Excel | Typical small-lab LIS (India) | PathLab Software |
|---|---|---|---|---|
| Case numbers per type and year | Manual, can repeat | Manual | Varies | Automatic, never repeat |
| Grossing templates by short code | Copy-paste | No | Report templates | .code + space, Tab to blanks |
| Block and slide log with location | Register | Sheet | Not shown publicly* | Auto-labelled, archive search |
| Second-opinion issue log | Register | Sheet | Not shown publicly* | Out / returned with filter |
| Bethesda categories as a field | Typed | Typed | Some formats | Pap and thyroid FNAC lists |
| TAT by case type vs target | No | Formulas | Varies | Median and P90, overdue badge |
| Signed, QR-verifiable report with addenda | No | No | QR on some | Yes, addenda shown as amended |
* As of November 2026, among the Indian products under ₹8,000 a month whose public material we reviewed, none showed case numbering, a block and slide log and cytology categories together; check with each vendor, as features change.
What it does not do
- No whole-slide imaging viewer or digital pathology.
- No cassette or slide-printer drivers; labels print as HTML from the browser.
- No voice dictation, and no CAP cancer protocols shipped; build your own synoptic checklists.
- IHC is logged as stain lines on the block, with no scoring module.
Pricing
Histopathology and cytology reporting, the block and slide log, labels, templates, addenda and TAT by case type are included in the Complete plan at ₹3,290 a month and Network at ₹6,490 a month, plus 18% GST, billed monthly. It is not part of the Essential plan. Compare every plan on the pricing page and see the other new modules on the features page.
Frequently asked questions
What is histopathology reporting software?
Histopathology reporting software tracks a tissue specimen from receipt to signed report: case number, gross description, blocks and slides, microscopy, diagnosis, sign-off and any addendum. PathLab Software also covers cytology (Pap smear, FNAC, fluids) with standard category lists and shows turnaround time by case type against your own targets.
What should a histopathology report contain?
A histopathology report should identify the patient, the case number and the specimen with its site and laterality, give the clinical details, the gross description with block key, the microscopic description, a clear diagnosis, any comments, and the pathologist's signature and date. Addenda after sign-off should be dated and visible on the report.
How are histopathology blocks and slides labelled and tracked?
Each block carries the case number and a block label, usually a letter for the container and a number for the cassette (A1, A2, B1). In PathLab Software blocks are labelled automatically, each has stains, slide count, status and archive location, and blocks sent for second opinion are logged out and back in.
Can Pap smear and FNAC cytology be reported in the same software?
Yes. In PathLab Software Pap smears and fluid cytology get C case numbers and FNACs get F numbers. Pap smears have an adequacy field and a category list from The Bethesda System for Reporting Cervical Cytology; thyroid FNACs have Bethesda thyroid categories I to VI. Categories print on the signed report.
How do grossing templates work?
A grossing template is a standard description with blanks. In PathLab Software you type a short code such as .gb followed by a space in the gross box and the gallbladder template appears; the Tab key jumps to each blank such as {size} or {wall} so you only type the measurements. Templates are your lab's own and editable.
Can the pathologist sign a histopathology report from a phone?
Yes. PathLab Software runs in a phone browser, so a pathologist can review the case, edit the diagnosis and sign with their login. The signed report gets a SHA-256 fingerprint and a QR verification code, exactly like routine reports, and is delivered through the usual channels.
How is an addendum added after a report is signed?
The pathologist adds a dated addendum on the case page. PathLab Software appends it to the report, marks the report amended, re-computes its fingerprint, writes an audit-trail entry and shows the report as amended on the QR verification page, so anyone holding the earlier copy can see a newer version exists.
Which PathLab Software plan includes histopathology?
Histopathology and cytology reporting with the block and slide log is included in the Complete plan at ₹3,290 a month and Network at ₹6,490, plus 18% GST, with monthly billing. It is not part of the Essential plan. Every plan starts with a 21-day free trial and free setup of your templates.
Move your histopathology register into the LIS
Start the 21-day free trial, or book a 20-minute walkthrough and we will load your grossing templates and case-number prefixes during the free setup.
